Inbred Mice
Origin:
In1980, Bosma found the mutation in C.B-17/lcr mice which were from Fox Chase cancer center.
Colour: Glabrous, albino
Features:
(1) Severe combined immunodeficiency (SCID)
(2) Mutation on Chromosome 16 which is responsible for deficient activity of an enzyme involved in DNA repair
(3) Impair the ability to make T or B lymphocytes, or activate some components of the complement system, and cannot fight infections, nor reject tumors and transplants efficiently
Ideal Research Fields:Immune system, cell transplantation strategies, virology, oncology, physiology, epidemiology, pathology of blood
Reference Data:
Mature Period (Male) |
6-8 weeks |
Mature Period (Female) |
6-8 weeks |
Mating Ratio |
1:2 |
Estrus Cycle |
3-5 days |
Pregnancy |
17-21 days |
Average Litter Size |
4-5 mice |
Birth Weight |
1-2g |
Weaning Weight (Male) |
9-12g |
Weaning Weight (Female) |
9-12g |
Lactation |
21 days |
Average Feed Consumption |
5g (per 100 g weight, per day) |
Average Water Consumption |
6-7 ml (per 100 g weight, per day) |
Feeding Temperature |
21±2℃ |
Relative Humidity |
40-70% |
Light Cycle |
12/12 hour |
Weight Loss During the Transit |
10% |
Ordering hotline: 020-81122060